ABSTRACT
Polycystic ovary syndrome (PCOS) is a common endocrine disease in women of childbearing age, which seriously affects women's reproductive health. In recent years, more and more studies have found that serum anti-Müllerian hormone (AMH) has certain significance in the diagnosis and treatment evaluation of PCOS. In addition, with the improvement of detection methods, more attention has been paid to the significance of female androgens and AMH in the evaluation of PCOS. This article reviews the recent research progress of serum AMH and androgens in the evaluation of PCOS.
Subject(s)
Female , Humans , Polycystic Ovary Syndrome/diagnosis , Androgens , Anti-Mullerian HormoneABSTRACT
Objective:To establish the fingerprint of standard decoction of Citri Reticulatae Pericarpium and evaluate its quality. Method:According to the preparation conditions of the standard decoction,15 batches of standard decoction of Citri Reticulatae Pericarpium were prepared.HPLC was employed to determine the content of hesperidin in this standard decoction.Ultraviolet spectroscopy(UV) and infrared spectroscopy(IR) were used to establish the fingerprint of standard decoction of Citri Reticulatae Pericarpium.The correlation coefficient method and double index sequence analysis method were used to compare and analyze the spectra of different batches of this standard decoction. Result:The content of hesperidin in 15 batches of this standard decoction were 0.82%-2.60%,and the measured value of dry extract rate was 32.02%-46.11%.Compared with ultraviolet and infrared control fingerprint,the fingerprint similarities of the standard decoction of each batch were > 0.897 and > 0.942,respectively.The double index analysis results showed that the common peak ratio was more than 62.50%,variation peak ratio was less than 46.67%. Conclusion:The quality evaluation method established in this study can be used for systematic evaluation of standard decoction of Citri Reticulatae Pericarpium,and it can provide theoretical reference for the formulation of quality standard of Citri Reticulatae Pericarpium dispensing granules and other related preparations.
ABSTRACT
<p><b>OBJECTIVE</b>To compare the therapeutic effects and safety of herpes zoster treated by the cotton sheet moxibustion combined with the plum-blossom-needle tapping therapy to western medicine.</p><p><b>METHODS</b>The multicentral random controlled method was adopted, 120 cases of herpes zoster were randomly divided into a comprehensive treatment group and a western medication group, 60 cases in each one. In the comprehensive treatment group, the tapping therapy of plum blossom needle was applied to the foci, corresponding Jiaji (EX-B 2), Quchi (LI 11), Waiguan (TE 5), Zusanli (ST 36), Taichong (LR 3), etc. Afterward, the cotton sheet moxibustion was given. In western medication group, Acyclovir ointment for external application, Valaciclovir Hydrochloride tablets and Vitamin B1 for oral administration were prescribed. In 7 days of treatment, the clinical symptom score, effect time, efficacy and safety were observed before and after treatment between two groups. The recurrence of disease was followed up for 1 month.</p><p><b>RESULTS</b>In the comprehensive treatment group, the cured rate and the total effective rate were 80.0% (48/60) and 98.3% (59/60) separately, which were significantly better than 45.0% (27/60) and 71.7% (43/60) in western medication group separately (P < 0.01, P < 0.05). After treatment, in either group, the scores of clinical symptoms such as pain rating index (PRI), Visual Analogue Scale (VAS), present pain intensity (PPI), skin lesion and sleeping score, etc. were all reduced significantly (P < 0.01, P < 0.05). The score reducing was much more obvious in the comprehensive treatment group (P < 0.01, P < 0.05). In the comprehensive treatment group, the time of pain stopping, the time of blister stopping, the time of scarring and the time of healing were all shorter tha tn those in western medication group (P < 0.01, P < 0.05). In the follow-up observation, 1 case (1.6%) was recurred in the comprehensive treatment group and 8 cases (13.3%) were in western medication group. In western medication group, 6 cases presented mild adverse reactions.</p><p><b>CONCLUSION</b>The cotton sheet moxibustion combined with the plum-blossom-needle tapping therapy is advantageous at good efficacy, quick effect and short-time treatment for herpes zoster, which is apparently superior to the treatment with Acyclovir ointment for external application, Valaciclovir Hydrochloride tablets and Vitamin B1 for oral administration. It is the safe and effective therapy.</p>
Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Young Adult , Herpes Zoster , Therapeutics , Moxibustion , Pain ManagementABSTRACT
<p><b>OBJECTIVE</b>To compare the differences in the clinical efficacy on tinnitus between the spinal balancing intervention and the conventional acupuncture.</p><p><b>METHODS</b>The randomized controlled trial were adopted. One hundred and twenty cases of tinnitus were randomized into a spinal balancing group and a conventional acupuncture group, 60 cases in each one. In the spinal balancing group, the comprehensive therapy of acu-puncture and Tuina was applied to the spine, the Back-shu points, Jiaji (EX-B 2), Tinggong (SI 19), Yifeng (TE 17), Fengchi (GB 20), Yuzhen (BL 9), Tianzhu (BL 10), etc. for the balancing intervention. In the conventional acupuncture group, acupuncture was applied to the local points and the points along the affected meridians. In each group, after 3 sessions of treatment, the degree of tinnitus and the accompanied symptoms were scored and compared before and after treatment. The comprehensive efficacy was assessed.</p><p><b>RESULTS</b>In the spinal balancing group, the clinical curative rate was 70.0% (42/60) and the total effective rate was 98.3% (59/60), which were significantly better than 45.0% (27/60) and 86.7% (52/60) in the conventional acupuncture group separately (P < 0.01, P < 0.05). After treatment, the degree of tinnitus and the accompanied symptom scores were all reduced in both groups (all P < 0.05), but the improvements in the spinal balancing group were better than those in the conventional acupuncture group (all P < 0.05). In 3-month follow-up visit after treatment, the recurrence rate in the spinal balancing group was lower than that in the conventional acupuncture group [5.1% (3/59) vs 13.5% (7/52)] (P < 0.05).</p><p><b>CONCLUSION</b>The spinal balancing intervention therapy relieves the symptoms of the patients with tinnitus remarkably. Its clinical efficacy is superior significantly to that of the conventional acupuncture and the recurrence rate is lower.</p>